He combined with Luis Suarez to compete a series of precision passes to give Uruguay the early advantage with a header in the seventh minute.
Ronaldo sliced another attempt wide and was booked for protesting after the referee declined to give a foul on Quaresma - but neither he nor Portugal could find a way through in four minutes of stoppage time as Uruguay held on to their lead to set up a quarterfinal against France on Friday.
"Now is not the time to talk about the future of players and coaches", Ronaldo said. "As the team captain I am proud of this group".
Cristiano Ronaldo refused to comment on his worldwide future following Portugal's exit at the FIFA World Cup 2018.
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Coming into the World Cup and at many times during the campaign as well, questions were raised over Portugal's reliance on their star striker.
Cristiano Ronaldo has never scored in the World Cup knockout stage. "He tried. The team didn't win because Uruguay scored twice". "Usually we also score". His shadows were Uruguay defenders Diego Godin and Jose Maria Gimenez, who know Ronaldo quite well from their clashes between Real Madrid and Atletico Madrid in the Spanish league.
But parity did not last long, Cavani steering a brilliant curling finish into the corner after 62 minutes following Bentancur's beautifully-weighted pass into his path.
Ronaldo was involved somewhat in Portugal's goal, even if he didn't come close to getting a touch on the cross.
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Cavani picked out Suarez on the left with a cross-field ball, before continuing his run into the penalty area and meeting the Barcelona striker's return delivery at the back post, the ball smacking off his face and flying in.
In the final moments of the half, with Suarez down following a challenge from Raphael Guerreiro, Portugal won a corner that came to nothing before a half-chance was steered wide by Cavani at the far post. "No team can win with one player alone", Santos said.
While Uruguay is advancing, it now must be concerned with the status of Cavani after he limped off the field and immediately called for a substitute.
7th minute. Goal. Uruguay.
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