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The White House condemned Iran's "provocative rocket attacks from Syria against Israeli citizens" and expressed strong support for "Israel's right to act in self-defence", while Russian Federation said the Israeli strikes marked a risky escalation, urging both Israel and Iran to avoid provoking each other.

Israel has vehemently opposed Iran's presence in Syria for fear of entrenching itself that close to its territory, which, coupled with the threat of Hezbollah in Lebanon, would represent a major blow to its security. "The US supports them and will support any action aimed at self-defense".

Where once the U.S. would have been the brake on spikes in Syrian violence, there is a real possibility President Donald Trump's withdrawal from the 2015 Iran nuclear deal is greasing the wheels towards a wider regional war.

Israel carried out the raids after it said around 20 rockets, either Fajr or Grad type, were fired from Syria at its forces in the occupied Golan Heights at around midnight. Four of the rockets were reported to have been intercepted by Iron Dome anti-missile systems; the other apparently fell short landing in Syrian territory.

Iran is trying to transfer state-of the-art weaponry, including the SA-22 (Pantsir-S1) air defense system and the Yakhont anti-ship cruise missile, from military storehouses in Syria to Hezbollah, Foreign Ministry director-general Dore Gold told The Jerusalem Post on Thursday from Berlin.

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In response, Israel launched attacks against much of Iran's military infrastructure in Syria.

Israeli Prime Minister Benjamin Netanyahu accused on Thursday Iran of crossing a "red line" in its attack against Israel from Syria. And it said that it's their duty to help those organizations that would fight Israel and would eventually bring Israel to its knees.

The attacks between Israel and Iran is enough evidence to show the world that we are one bomb away from a full-blown war.

The Iranians have deployed in Syria along with Iran-backed Shi'ite militias and Russian troops to support President Bashar al-Assad in the country's civil war. The barrage of missiles killed three soldiers while injuring another two, the Syrian MoD said.

Israel said Thursday it hit "almost all" of Iran's infrastructure sites during dozens of airstrikes overnight in Syria. Israel says its occasional strikes in Syria aim to foil that.

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The subsequent Israeli air strikes killed 23 pro-government fighters in Syria, according to the UK-based Syrian Observatory for Human Rights. He added that "ground assets were also used to strike into Syria".

The military escalation comes at a worrying time, after the USA pulled out of the Iran nuclear deal with active support from the Israeli government.

In February, Israel shot down what it said was an armed Iranian drone that entered Israeli airspace. Iran has vowed to retaliate.

The two sides have been on a collision course for months.

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