It has always been a matter of time before City formally clinch the title but next week's opponents head into the derby in second place and with a win under their belt after beating Swansea City 2-0 at Old Trafford.
Since joining United from Atletico Madrid as a talented but nervy shot-stopper back in 2011, De Gea has played 307 times for the club and transformed into a true world-class star.
'First half they didn't cross the midfield line, didn't have one shot.
Huddersfield Town remained in trouble, three points above relegation, after losing 1-0 at Newcastle United to a goal by Ayoze Perez.
The goal was Lukaku's 100th in the Premier League, he therefore became the quickest foreign player to achieve this feat.
Salah Strikes Again To Move Liverpool Into Second Spot
The league's leading scorer kept his cool to convert Andrew Robertson's cross on 84 minutes for his 29th goal of the season. Andy Robertson absolutely loved Mohamed Salah's late victor for Liverpool at Crystal Palace.
"I'll stay positive and still try and take my chances".
The Chile worldwide made it 2-0 for United in the 20th minute after Jesse Lingard cut open the City defence with an incisive pass that found Sanchez, who slotted into the bottom corner from 18-yards out. The first half [was] probably one of the best we played here.
That being said, United turned on the style on Saturday.
Sanchez's work-rate faded prior to his substitution during the second period, and Mourinho said the Chilean suffered physically after featuring in the friendlies for Chile.
"I was drugged" Miguna speaks after deported to Dubai
He shared photos of himself and his swollen hand, as he lied in a hospital bed moments after arriving at the Dubai Airport. I want to take a flight only to Nairobi. "I have not been given access to my lawyers, family members and physicians".
United were dominant, Nemanja Matic solid, Juan Mata finding and exploiting space from the right, Pogba creating - or attempting to - in the middle and Lingard, who scored two exceptional goals at Swansea in October, effective in the No 10 role.
He does at least give The Swans credit for our fightback in the second half. "The manager told us we all have to fight for our place in the team".
"The team played very well in the first half so Alexis played well, but I think everybody played really well in the first half".
"Some players played midweek, they arrived late, tired, they felt the game was in the pocket and in the second half they let it go a bit".
FRANCE ON LOCKDOWN: 'Car ploughs into soldiers outside barracks' - huge manhunt launched
French police are hunting for a driver who tried to run over several soldiers outside an army base in southeast France . The incident comes as victims of a hostage-taking at a supermarket in the south-western town of Trèbes are being buried.